Mitochondrial fission is increased in macrophages during mROS production in response to S. pneumoniae
M. Mohasin, K. Balbirnie-Cumming, E. Fisk, E. C. Prestwich, C. D. Russell, J. Marshall, C. Pridans, S. P. Allen, P. J. Shaw, K. J. De Vos, C. J. Hill, P. Bullough, A. M. Condliffe, T. J. Mitchell, H. M. Marriott, D. H. Dockrell
This study shows that mitochondrial fission in macrophages increases during mROS production in response to S. pneumoniae, linked to reduced oxidative phosphorylation and enhanced bacterial killing.
bioRxiv · Nov 16, 2021 · PreprintImmunology