Author

C. Pridans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. C. Bain· 2 shared A. Hidalgo· 1 shared A. J. Simpson· 1 shared A. L. Johnson· 1 shared A. M. Condliffe· 1 shared A. Rostron· 1 shared A. S. Mirchandani· 1 shared A. Todica· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

C. C. Bain

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia

T. Weinberger, D. Messerer, M. Joppich, M. Fischer, C. Garcia, K. Kumaraswami, V. Wimmler, S. Ablinger, S. Raeuber, J. Fang, L. Liu, W. H. Liu, J. Winterhalter, J. Lichti, L. Tomas, , C. Schulz

This study shows resident macrophages improve cardiac remodelling while recruited macrophages influence infarct size after myocardial ischemia/reperfusion injury.

bioRxiv · May 8, 2023Immunology

CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration following radiation-induced injury

J. G. McKendrick, G.-R. Jones, S. S. Elder, E. Mercer, M. S. Magalhaes, C. Rocchi, L. M. Hegarty, A. L. Johnson, C. Schneider, B. Becher, C. Pridans, N. A. Mabbott, Z. Liu, F. Ginhoux, M. Bajenoff, , E. Emmerson

This study identifies CSF1R-dependent macrophages as critical for epithelial regeneration after radiation-induced salivary gland injury.

bioRxiv · Jun 12, 2022Immunology

Hypoxia shapes the immune landscape in lung injury promoting inflammation persistence

A. S. Mirchandani, S. J. Jenkins, C. C. Bain, H. Lawson, P. Coelho, F. Murphy, D. Griffith, A. Zhang, M. A. Sanchez-Garcia, L. Reyes, T. Morrison, S. Arienti, P. Sadiku, E. Watts, R. Dickinson, , S. Walmsley

This study shows hypoxia suppresses type I interferon signaling in ALI, leading to monocytopenia and unchecked inflammation, which can be mitigated by CSF1 administration.

bioRxiv · Mar 11, 2022 · PreprintCell Biology

Mitochondrial fission is increased in macrophages during mROS production in response to S. pneumoniae

M. Mohasin, K. Balbirnie-Cumming, E. Fisk, E. C. Prestwich, C. D. Russell, J. Marshall, C. Pridans, S. P. Allen, P. J. Shaw, K. J. De Vos, C. J. Hill, P. Bullough, A. M. Condliffe, T. J. Mitchell, H. M. Marriott, D. H. Dockrell

This study shows that mitochondrial fission in macrophages increases during mROS production in response to S. pneumoniae, linked to reduced oxidative phosphorylation and enhanced bacterial killing.

bioRxiv · Nov 16, 2021 · PreprintImmunology