Author

E. Fullam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

C. S. Guy· 3 shared J. Angulo· 2 shared A. D. Cameron· 1 shared C. de Wolf· 1 shared C. M. Brown· 1 shared C. M. Furze· 1 shared G. West· 1 shared J. A. Gott· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBiochemistry

C. S. Guy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Fluorinated trehalose analogues for cell surface engineering and imaging of Mycobacterium tuberculosis

C. S. Guy, J. A. Gott, J. Ramirez-Cardenas, C. de Wolf, C. M. Furze, G. West, J. C. Munoz-Garcia, J. Angulo, E. Fullam

This paper develops fluorinated trehalose analogues to label and visualize Mycobacterium tuberculosis, showing their uptake correlates with substrate recognition and enabling pathogen-specific detection.

bioRxiv · Jan 30, 2024 · PreprintMicrobiology

From Molecular Dynamics to Supramolecular Organization: The Role of PIM Lipids in the Originality of the Mycobacterial Plasma Membrane

C. M. Brown, R. A. Corey, Y. Gao, Y. K. Choi, M. Gilleron, N. Destainville, E. Fullam, W. Im, P. J. Stansfeld, M. Chavent

This paper uses molecular dynamics simulations to study the role of PIM lipids in the structure and organization of the Mycobacterial plasma membrane and validates findings with drug testing.

bioRxiv · Jun 29, 2022Biophysics

Structural basis of glycerophosphodiester recognition by the Mycobacterium tuberculosis substrate-binding protein UgpB

J. Fenn, R. Nepravishta, C. S. Guy, J. Harrison, J. Angulo, A. D. Cameron, E. Fullam

This study determines the structure of Mtb UgpB bound to GPC and shows it recognizes other glycerophosphodiesters, enhancing understanding of nutrient scavenging in tuberculosis.

bioRxiv · Jan 28, 2019Biochemistry

Targeting extracellular glycans: Tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis

C. S. Guy, M. I. Gibson, E. Fullam

This study designs multimeric boronic acids that selectively kill Mycobacterium tuberculosis by targeting its unique extracellular glycans, achieving high selectivity and low cytotoxicity.

bioRxiv · Jan 24, 2019Biochemistry