Cancer BiologybioRxivPreprint
PTEN mutant NSCLC require ATM to suppress pro-apoptotic signalling and evade radiotherapy
T. Fischer, O. Hartmann, M. Reissland…·M. E. Diefenbacher
This study shows PTEN-deficient NSCLC cells rely on ATM to repair radiation damage and resist therapy, and ATM inhibition synergizes with radiation in these models.