Author

K. Klann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. Muench· 2 shared C. Prieto-Garcia· 2 shared C. Schuelein-Voelk· 2 shared M. E. Diefenbacher· 2 shared M. Reissland· 2 shared M. Rosenfeldt· 2 shared O. Hartmann· 2 shared T. Fischer· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. Muench

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PTEN mutant NSCLC require ATM to suppress pro-apoptotic signalling and evade radiotherapy

T. Fischer, O. Hartmann, M. Reissland, C. Prieto-Garcia, K. Klann, C. Schuelein-Voelk, B. Polat, E. Gebhard-Hartmann, M. Rosenfeldt, C. Muench, M. Flentje, M. E. Diefenbacher

This study shows PTEN-deficient NSCLC cells rely on ATM to repair radiation damage and resist therapy, and ATM inhibition synergizes with radiation in these models.

bioRxiv · Jul 24, 2021 · PreprintCancer Biology

Inhibition of USP28 overcomes Cisplatin-Resistance of Squamous Tumors by Suppression of the Fanconi Anemia Pathway.

C. Prieto-Garcia, O. Hartmann, M. Reissland, T. Fischer, C. R. Maier, M. Rosenfeldt, C. Schuelein-Voelk, K. Klann, R. Kalb, I. Dikic, C. Muench, M. E. Diefenbacher

This study identifies USP28 inhibition as a strategy to overcome cisplatin resistance in squamous cell carcinomas by suppressing the Fanconi Anemia DNA repair pathway.

bioRxiv · Sep 10, 2020Cancer Biology