Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells
A. V. Makela, A. Tundo, H. V. Liu, D. Schneider, T. Hermiston, P. Khodakivskyi, E. Goun, C. H. Contag
This study demonstrates targeted intracellular delivery of molecular cargo to hypoxic breast cancer stem cells using GlaS, a protein that binds phosphatidylserine and delivers payloads under hypoxic conditions.
bioRxiv · Jan 12, 2024Cancer Biology