Author

E. Helle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Dainis· 1 shared B. Thebaud· 1 shared B. Vanderhyden· 1 shared C. Cyr-Depauw· 1 shared D. P. Cook· 1 shared E. Mervaala· 1 shared E. Temmes· 1 shared F. Lesage· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Dainis

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Author profile →

2 papers

Recent·Most cited

Modeling cellular crosstalk and organotypic vasculature development with human iPSC-derived endothelial cells and cardiomyocytes

E. Helle, M. Ampuja, A. Dainis, L. Antola, E. Temmes, E. Mervaala, R. Kivela

This study uses hiPSC-derived cells to show coculture with cardiomyocytes and flow-induced shear stress alter endothelial cell transcriptomes, revealing cardiac endothelial identity and novel crosstalk mechanisms.

bioRxiv · May 4, 2020 · PreprintCell Biology

Multiplexed single-cell transcriptomic analysis of normal and impaired lung development in the mouse

M. K. Hurskainen, I. Mizikova, D. P. Cook, C. Cyr-Depauw, F. Lesage, N. Andersson, E. Helle, L. Renesme, R. P. Jankov, M. Heikinheimo, B. Vanderhyden, B. Thebaud

The paper uses scRNA-seq to analyze lung development in mice under normal and hyperoxic conditions, identifying cellular changes linked to bronchopulmonary dysplasia.

bioRxiv · Dec 22, 2019 · PreprintCell Biology