Cell BiologybioRxivPreprint
Modeling cellular crosstalk and organotypic vasculature development with human iPSC-derived endothelial cells and cardiomyocytes
E. Helle, M. Ampuja, A. Dainis…·R. Kivela
This study uses hiPSC-derived cells to show coculture with cardiomyocytes and flow-induced shear stress alter endothelial cell transcriptomes, revealing cardiac endothelial identity and novel crosstalk mechanisms.