Author

E. Karakoc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

A. Cakir· 1 shared A. G. O. Demir· 1 shared A. Mardinoglu· 1 shared A. R. Bassett· 1 shared B. E. Kerman· 1 shared C. Dincer· 1 shared C. Hardy· 1 shared C. M. Cattaneo· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Cakir

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hexokinase 1b is a novel target for non-small-cell lung cancer

Y. Yozgat, E. Karakoc, O. Sahin, S. Cimen, W. M. Rabeh, M. S. Aydin, A. Mardinoglu, I. Gursel, A. Cakir, O. Sensoy, E. M. Ozdemir, Y. Bayrak, M. Z. Gunluoglu, O. Saatci, J. Jabbar, , M. A. Cevher

This study identifies HK1b as a novel therapeutic target in NSCLC by showing its role in glycolysis, tumor progression, and cisplatin resistance.

bioRxiv · Jun 27, 2022 · PreprintCancer Biology

Base editing screens map mutations affecting IFNγ signalling in cancer

M. A. Coelho, E. Karakoc, S. G. Bhosle, E. Goncalves, T. Burgold, S. Cooper, C. M. Cattaneo, V. Veninga, S. Consonni, C. Dincer, S. F. Vieira, F. Gibson, S. Barthorpe, C. Hardy, J. Rein, , M. J. Garnett

This study uses base editing to identify mutations affecting IFNγ signalling in cancer, revealing loss- and gain-of-function variants with clinical relevance.

bioRxiv · Mar 29, 2022 · PreprintCancer Biology

Engineering recombination between diverged yeast species reveals genetic incompatibilities

G. O. Bozdag, J. Ono, J. A. Denton, E. Karakoc, N. Hunter, J.-Y. Leu, D. Greig

The paper suppresses meiotic recombination in yeast hybrids to identify genetic incompatibilities causing sterility.

bioRxiv · Sep 5, 2019 · PreprintEvolutionary Biology