Reduced PABPN1 levels causes cytoskeleton disorganization and aberrant differentiation
V. Raz, E. van der Wal, C. Domagoj, C. S. Olie, L. Maton, J. C. de Greef, I.-H. Lin, Y.-F. Chen, E. Kareem, J. M. Penninger, B. Kessler
This study shows that reduced PABPN1 levels disrupt cytoskeletal organization and impair muscle differentiation, with actin overexpression improving these defects.
bioRxiv · Jan 15, 2020 · PreprintCell Biology