Understanding the biosynthesis of human IgMs through a combinatorial expression of mutant subunits that affect different assembly steps
H. Hasegawa, S. Wang, E. Kast, H.-T. Chou, M. Kaur, T. Janlaor, M. Mostafavi, Y.-L. Wang, P. Li
This study investigates IgM biosynthesis by analyzing mutant subunits affecting disulfide bonds, revealing the role of non-covalent interactions in IgM assembly and secretion.
bioRxiv · Sep 1, 2023 · PreprintCell Biology