The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells
C. Noyes, S. Kitajima, F. Li, Y. Suita, S. Miriyala, S. Isaac, N. Ahsan, E. Knelson, A. Vajdi Hoojghan, T. Tani, T. Thai, D. Xu, J. Murai, N. Tapinos, C. Takahashi, , M. Yajima
This study shows DDX4, a germline factor, enhances chemoresistance and motility in SCLC cells by altering metabolism and EMT-like features.
bioRxiv · Apr 22, 2022Cancer Biology