Author

D. Barbie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Näätänen· 1 shared A. Vajdi Hoojghan· 1 shared B. Ghimire· 1 shared C. Noyes· 1 shared C. S. Mitsiades· 1 shared C. Takahashi· 1 shared C. Zhang· 1 shared D. A. Lee· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

A. Näätänen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Patient-Specific Vascularized Tumor Model: Blocking TAM Recruitment with Multispecific Antibodies Targeting CCR2 and CSF-1R

H. T. Nguyen, N. Gurvich, M. R. Gillrie, G. Offeddu, M. Humayun, E. L. Kan, Z. Wan, M. F. Coughlin, C. Zhang, V. Vu, S. W. L. Lee, S.-L. Tan, D. Barbie, J. Hsu, R. D. Kamm

This paper develops a vascularized tumor model to study TAM recruitment and evaluates a multispecific antibody's effect on monocyte migration and TAM repolarization.

bioRxiv · Nov 28, 2023Bioengineering

Single-cell functional genomics of natural killer cell evasion in blood cancers

O. Dufva, S. Gandolfi, J. Huuhtanen, O. Dashevsky, K. Saeed, J. Klievink, P. Nygren, J. Bouhlal, J. Lahtela, A. Näätänen, B. Ghimire, T. Hannunen, P. Ellonen, H. Duan, J. Theodoropoulos, , S. Mustjoki

The paper uses single-cell and genome-scale functional genomics to study how blood cancer cells evade NK cells, identifying key genes and pathways involved in resistance and sensitivity.

bioRxiv · Aug 22, 2022 · PreprintImmunology

The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells

C. Noyes, S. Kitajima, F. Li, Y. Suita, S. Miriyala, S. Isaac, N. Ahsan, E. Knelson, A. Vajdi Hoojghan, T. Tani, T. Thai, D. Xu, J. Murai, N. Tapinos, C. Takahashi, , M. Yajima

This study shows DDX4, a germline factor, enhances chemoresistance and motility in SCLC cells by altering metabolism and EMT-like features.

bioRxiv · Apr 22, 2022Cancer Biology