PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.
N. M. Wickramasinghe, D. Sachs, B. Shewale, D. M. Gonzalez, P. Dhanan-Krishnan, D. Torre, E. LaMarca, S. Raimo, R. Dariolli, M. Serasinghe, J. Mayourian, R. Sebra, K. G. Beaumont, R. Iyengar, D. L. French, , N. C. Dubois
This study shows that activating PPARD signaling enhances metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.
bioRxiv · Jul 12, 2021 · PreprintCell Biology