Author

A. Hansen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Ecology· 2 Pharmacology & Toxicology· 2 Genetics· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 6 Research Focus:cell type annotation· 5 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:ecology & biodiversity· 2 Assay:imaging· 2 Approach:statistical model· 2

Frequent Co-Authors

T. Eschenhagen· 5 shared H. S. Grantham· 2 shared O. Venter· 2 shared P. Jantz· 2 shared S. Goetz· 2 shared U. Saleem· 2 shared A. DeGemmis· 1 shared A. Dendorfer· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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5 shared papersPharmacology & Toxicology

T. Eschenhagen

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

A critical role of retinoic acid concentration for the induction of a fully human-like atrial phenotype in hiPSC-CM

C. Schulz, M. Soenmez, J. Krause, E. Schwedhelm, P. Bangfen, D. Alihodzic, A. Hansen, T. Eschenhagen, T. Christ

This study shows that 1 μM retinoic acid is necessary and sufficient to induce a fully human-like atrial phenotype in hiPSC-CMs, overcoming methodological challenges in RA concentration control.

bioRxiv · Jan 3, 2023 · PreprintPharmacology & Toxicology

LILRB1 and LILRB2 expression in peripheral blood immune cells at 18 and 24 months of age in infants born from mothers with placental malaria

C. Dechavanne, O. Nouatin, R. Adamou, S. Edslev, A. Hansen, F. Meurisse, I. Sadissou, E. Gbaguidi, J. Milet, G. Cottrell, L. Gineau, A. Sabbagh, A. Massougbodji, K. Moutairou, E. A. Donadi, , D. Courtin

This study examines LILRB1 and LILRB2 expression in immune cells of infants born to mothers with placental malaria, finding lower non-classical monocytes and higher LILRB2 expression associated with increased malaria susceptibility.

bioRxiv · Oct 26, 2021 · PreprintImmunology

PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.

N. M. Wickramasinghe, D. Sachs, B. Shewale, D. M. Gonzalez, P. Dhanan-Krishnan, D. Torre, E. LaMarca, S. Raimo, R. Dariolli, M. Serasinghe, J. Mayourian, R. Sebra, K. G. Beaumont, R. Iyengar, D. L. French, , N. C. Dubois

This study shows that activating PPARD signaling enhances metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.

bioRxiv · Jul 12, 2021 · PreprintCell Biology

Human engineered heart tissue transplantation in a guinea pig chronic injury model

C. von Bibra, A. Shibamiya, B. Geertz, E. Querdel, M. Koehne, T. Stuedemann, J. Starbatty, A. Hansen, B. Hiebl, T. Eschenhagen, F. Weinberger

This study transplants human engineered heart tissue (EHT) into chronically injured guinea pig hearts and finds limited functional improvement despite engraftment.

bioRxiv · Jun 28, 2021Pharmacology & Toxicology

SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes

D. Bojkova, J. Wagner, M. Shumliakivska, G. Aslan, U. Saleem, A. Hansen, G. Luxan, S. Guenther, M. D. Pham, J. Krishnan, P. Harter, U. Ermel, A. S. Frangakis, A. Zeiher, H. Milting, , S. Dimmeler

This study shows SARS-CoV-2 infects human cardiomyocytes, causing cytotoxicity and apoptosis, and confirms this in cardiac tissue models.

bioRxiv · Jun 1, 2020Cell Biology

Change in terrestrial human footprint drives continued loss of intact ecosystems

B. A. Williams, O. Venter, J. R. Allan, S. Atkinson, J. A. Rehbein, M. S. Ward, M. Di Marco, H. S. Grantham, J. Erivin, S. Goetz, A. Hansen, P. Jantz, R. Pillay, S. Rodriguez-Buritica, C. Supples, , J. E. M. Watson

The paper maps changes in the terrestrial human footprint from 2000 to 2013, showing a significant loss of intact ecosystems, particularly in tropical and subtropical regions.

bioRxiv · May 4, 2020Ecology

Modification of forests by people means only 40% of remaining forests have high ecosystem integrity

H. S. Grantham, A. Duncan, T. D. Evans, K. R. Jones, H. Beyer, R. Schuster, J. Walston, J. Ray, J. Robinson, M. Callow, T. Clements, H. Costa, A. DeGemmis, P. R. Elsen, J. Ervin, , S. Wang

The paper quantifies global forest modification, finding 40.5% of remaining forests have high ecosystem integrity, mostly in specific regions, and highlights the need for policies to protect these areas.

bioRxiv · Mar 5, 2020 · PreprintEcology

Variation in the plasma membrane monoamine transporter (PMAT, encoded in SLC29A4) and organic cation transporter 1 (OCT1, encoded in SLC22A1) and gastrointestinal intolerance to metformin in type 2 diabetes: an IMI DIRECT study

Adem Y. Dawed, Kaixin Zhou, Nienke van Leeuwen, Anubha Mahajan, Neil Robertson, Robert Wilhelm Koivula, Petra J. M. Elders, Simone P. Rauh, Angus G. Jones, Reinhard Walter Holl, Julia Stingl, Paul W. Franks, Mark I. McCarthy, Leen M. ‘t Hart, Ewan R. Pearson, , A. Forman

This study investigates the association between genetic variants in PMAT and OCT1 transporters and metformin gastrointestinal intolerance in type 2 diabetes patients.

Diabetes Care · Mar 18, 2019Peer-reviewedGenetics

Versatile open software to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo

L. Sala, B. J. van Meer, L. G. J. Tertoolen, J. Bakkers, M. Bellin, R. Davis, C. Denning, M. A. E. Dieben, T. Eschenhagen, E. Giacomelli, C. Grandela, A. Hansen, E. R. Holman, M. R. M. Jongbloed, S. M. Kamel, , F. L. Burton

MUSCLEMOTION quantifies cardiac contraction in vitro and in vivo, providing reliable pharmacological and disease phenotype data across multiple models.

bioRxiv · Jul 8, 2017Physiology