SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation
M. S. Marks, L. Le, I. E. Escobar, T. Ho, A. J. Lefkovith, E. Latteri, K. D. Haltaufderhyde, E. V. Sviderskaya, D. C. Bennett, E. Oancea, M. K. Dennis
This study identifies SLC45A2's role in melanosome pH regulation and pigmentation, showing its function in melanin synthesis and how a variant affects protein stability and pigmentation.
bioRxiv · Mar 3, 2020Cell Biology