E. Levanon

Dissecting the basis for differential substrate specificity of ADAR1 and ADAR2

This study investigates how secondary structure influences ADAR1 and ADAR2 substrate specificity through synthetic sequence analysis and structural disruption experiments.

Disrupted RNA editing in beta cells mimics early stage type 1 diabetes

Disrupted RNA editing in beta cells leads to an interferon response and diabetes, mimicking early-stage type 1 diabetes without viral infection.