Zn2+ potentiation of OTOP proton channels identifies structural elements of the gating apparatus
B. Teng, J. Kaplan, Z. Liang, M. P. Goldschen-Ohm, E. Liman
This paper identifies structural elements in the OTOP channel family that mediate Zn2+ activation, revealing the tm 11-12 linker as part of the gating apparatus.
bioRxiv · Dec 15, 2022Biophysics