Author

B. Teng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Assay:electrophysiology· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. B. Ward· 2 shared E. Liman· 2 shared J. Kaplan· 2 shared Y.-H. Tu· 2 shared Z. Liang· 2 shared A. K. Pingili· 1 shared A. Rich· 1 shared B. Burendei· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiophysics

A. B. Ward

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Zn2+ potentiation of OTOP proton channels identifies structural elements of the gating apparatus

B. Teng, J. Kaplan, Z. Liang, M. P. Goldschen-Ohm, E. Liman

This paper identifies structural elements in the OTOP channel family that mediate Zn2+ activation, revealing the tm 11-12 linker as part of the gating apparatus.

eLife · Apr 13, 2023Peer-reviewedBiophysics

Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery

L. M. Sipe, M. Chaib, E. B. Korba, M. C. Lovely, H. Jo, B. R. Counts, U. Tanveer, J. C. Clements, N. A. John, D. Daria, T. N. Marion, R. Sekhri, A. K. Pingili, B. Teng, J. A. Carson, , L. Makowski

This study shows that bariatric surgery followed by immune checkpoint blockade improves breast cancer outcomes in formerly obese mice, despite weight loss being less effective than diet in reducing tumor burden.

bioRxiv · Mar 30, 2022Cancer Biology

Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels

B. Teng, J. Kaplan, Z. Liang, Z. Krieger, Y.-H. Tu, B. Burendei, A. B. Ward, E. Liman

This study identifies structural motifs in OTOP channels that determine subtype-specific pH sensitivity, showing that proton gating is mediated by extracellular linkers in the N and C domains.

bioRxiv · Mar 1, 2022Biophysics

Dynamic Detection and Reversal of Myocardial Ischemia Using an Artificially Intelligent Bioelectronic Medicine

P. D. Ganzer, M. S. Loeian, S. R. Roof, B. Teng, L. Lin, D. A. Friedenberg, I. W. Baumgart, E. C. Meyers, K. S. Chun, A. Rich, W. W. Muir, D. J. Weber, R. L. Hamlin

This study uses artificial neural networks to detect and reverse myocardial ischemia through bioelectronic medicine, achieving high accuracy and effective biomarker reversal.

bioRxiv · Dec 30, 2020 · PreprintBioengineering

Structures of the Otopetrin Proton Channels Otop1 and Otop3

K. Saotome, B. Teng, C. C. Tsui, W.-H. Lee, Y.-H. Tu, M. S. P. Sansom, E. R. Liman, A. B. Ward

The paper reports cryo-EM structures of zebrafish Otop1 and chicken Otop3, revealing their dimeric architecture and potential proton conduction pathways.

bioRxiv · Feb 6, 2019Biochemistry