Author

E. M. Barros

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. I. Johnston· 1 shared D. P. Harkin· 1 shared E. E. Parkes· 1 shared K. I. Savage· 1 shared K. Lappin· 1 shared N. McCabe· 1 shared R. Ali· 1 shared R. D. A. Wilkinson· 1 shared

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2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

D. I. Johnston

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintOct 24, 2019

Topoisomerase II inhibitors induce cGAS-STING dependent inflammation resulting in cytokine induction and immune checkpoint activation

R. D. A. Wilkinson, N. McCabe, E. E. Parkes…·K. I. Savage

This study shows topo-II inhibitors like doxorubicin induce cGAS-STING dependent inflammation, cytokine production, and immune checkpoint activation in cancer cells, enhancing potential for immune checkpoint blockade therapy.

DOI 10.1101/764662

humanbulk RNA-seq

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