Author

E. M. Patrick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:yeast· 1

Frequent Co-Authors

J. C. Schmidt· 2 shared M. J. Comstock· 2 shared A. A. Putnam· 1 shared B. Payne· 1 shared B. S. Al-Masraf· 1 shared E. Jankowsky· 1 shared G. I. Perez· 1 shared J. Slivka· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

J. C. Schmidt

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Author profile →

3 papers

Recent·Most cited

High-resolution fleezers reveal duplex opening and stepwise assembly by an oligomer of the DEAD-box helicase Ded1p

E. M. Patrick, R. Yadav, K. Senanayake, K. Cotter, A. A. Putnam, E. Jankowsky, M. J. Comstock

This study uses high-resolution optical tweezers to show Ded1p oligomers unwind RNA duplexes in 4-6 bp steps through dynamic protomer assembly and ATP hydrolysis.

bioRxiv · Feb 29, 2024Biophysics

TCAB1 prevents nucleolar accumulation of the telomerase RNA to promote telomerase assembly

B. S. Al-Masraf, G. I. Perez, E. M. Patrick, K. Adams-Boone, S. B. Cohen, L. Han, K. Yu, J. C. Schmidt

This study shows that TCAB1 prevents telomerase RNA from accumulating in the nucleolus, which is necessary for telomerase assembly.

bioRxiv · May 27, 2021 · PreprintCell Biology

Mechanism of processive telomerase catalysis revealed by high-resolution optical tweezers

E. M. Patrick, J. Slivka, B. Payne, M. J. Comstock, J. C. Schmidt

This study uses optical tweezers to show how telomerase binds DNA and synthesizes telomeric repeats, revealing the mechanism of processive telomerase catalysis.

bioRxiv · Aug 23, 2019Biochemistry