Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
O. Belan, C. Barroso, A. Kaczmarczyk, R. Anand, S. Federico, N. O'Reilly, M. D. Newton, E. Maeots, R. I. Enchev, E. Martinez-Perez, D. S. Rueda, S. J. Boulton
The paper uses single-molecule imaging to show how BRC-2 and RFS-1/RIP-1 mediate RAD-51 filament nucleation and growth during homologous recombination.
bioRxiv · Nov 5, 2020Biophysics