Author

E. Mangialardi

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

G. T. Saffi· 1 shared J. Vacher· 1 shared L. SALMENA· 1 shared R. J. Botelho· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

G. T. Saffi

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1 paper

Recent·Most cited

Cell BiologybioRxivDec 13, 2021

PIKfyve inhibition reveals a novel role for Inpp4b in the regulation of PtdIns(3)P and lysosome dynamics

G. T. Saffi, E. Mangialardi, J. Vacher…·L. SALMENA

This study identifies a novel crosstalk between Inpp4b and PIKfyve that regulates lysosome membrane phosphoinositide composition and homeostasis by restricting VPS34-dependent PtdIns(3)P production.

DOI 10.1016/j.jbc.2022.102187

mouseexperimental assay