Author

E. Marra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

G. Roscilli· 3 shared L. Luberto· 3 shared M. Maffei· 3 shared A. M. Anastasi· 2 shared A. Muzi· 2 shared A. Riccio· 2 shared A. Rosi· 2 shared A. Rossi· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

G. Roscilli

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Relevance of the viral Spike protein/cellular Estrogen Receptor-α interaction for endothelial-based coagulopathy induced by SARS-CoV-2

S. S. Barbieri, F. Cattani, L. Sandrini, M. M. Grillo, C. Talarico, D. Iaconis, L. Lione, E. Salvatori, P. Amadio, G. Garoffolo, M. Maffei, F. Galli, A. R. Beccari, E. Marra, M. Zoppi, , M. Pesce

This study investigates how the SARS-CoV-2 Spike protein interacts with the estrogen receptor-α to enhance pro-coagulant activity in endothelial cells, leading to thrombosis risk.

bioRxiv · Oct 4, 2022 · PreprintCell Biology

Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery

F. M. Milazzo, A. Chaves-Sanjuan, O. Minenkova, D. Santapaola, A. M. Anastasi, G. Battistuzzi, C. Chiapparino, A. Rosi, E. Merlo Pich, C. Albertoni, E. Marra, L. Luberto, C. Viollet, L. G. Spagnoli, A. Riccio, , R. De Santis

The paper shows that scFv76 antibody neutralizes multiple SARS-CoV-2 variants and reduces lung damage in mice when delivered via aerosol.

bioRxiv · May 27, 2022Microbiology

The nuts and bolts of SARS-CoV-2 Spike Receptor Binding Domain heterologous expression

M. Maffei, L. C. Montemiglio, G. Vitagliano, L. Fedele, S. Sellathurai, F. Bucci, M. Compagnone, V. Chiarini, C. Exertier, A. Muzi, G. Roscilli, B. Vallone, E. Marra

This paper characterizes the stability and functionality of SARS-CoV-2 RBD produced in three expression systems using biophysical and functional assays.

bioRxiv · Sep 17, 2021Biochemistry

COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19

A. Conforti, E. Marra, F. Palombo, G. Roscilli, M. Rava, V. Fumagalli, A. Muzi, M. Maffei, L. Luberto, L. Lione, E. Salvatori, M. Compagnone, E. Pinto, E. Pavoni, F. Bucci, , De F

This paper evaluates a DNA vaccine candidate, COVID-eVax, which induces strong neutralizing antibodies and T cell responses against SARS-CoV-2 in animal models, showing protective effects against viral challenge.

bioRxiv · Jun 14, 2021 · PreprintImmunology

Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy

O. Minenkova, D. Santapaola, F. M. Milazzo, A. M. Anastasi, G. Battistuzzi, C. Chiapparino, A. Rosi, G. Gritti, G. Borleri, A. Rambaldi, C. Dental, C. Viollet, B. Pagano, L. Salvini, E. Marra, , R. De Santis

This study identifies human antibody fragments that neutralize SARS-CoV-2 variants and show efficacy in animal models, suggesting potential for early COVID-19 therapy.

bioRxiv · Jun 4, 2021Bioengineering