E. Pinto

Immunogenicity of COVID-eVax Is Moderately Impacted by Temperature and Molecular Isoforms

This study shows that the immunogenicity of the plasmid DNA vaccine COVID-eVax is not significantly affected by temperature or DNA isoform changes.

A linear SARS-CoV-2 DNA vaccine candidate reduces virus shedding in ferrets

This study evaluates a linear SARS-CoV-2 DNA vaccine delivered via electroporation in ferrets, showing reduced virus shedding and immune responses.

A linear DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain elicits protective immunity in domestic cats

This study evaluates a linear DNA vaccine in domestic cats, showing it is safe and induces immune responses against SARS-CoV-2.

Linear DNA amplicons as a novel cancer vaccine strategy

This study develops PCR-produced DNA amplicons as a cancer vaccine strategy, showing they elicit immune responses and reduce tumor growth when combined with immune-checkpoint inhibitors.

COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19

This paper evaluates a DNA vaccine candidate, COVID-eVax, which induces strong neutralizing antibodies and T cell responses against SARS-CoV-2 in animal models, showing protective effects against viral challenge.

L-DOPA dioxygenase of the fly agaric toadstool: revision of the dodA gene sequence and mechanism of enzymatic pigment production

The paper revises the dodA gene sequence of Amanita muscaria and describes the mechanism of AmDODA, a promiscuous dioxygenase that produces betalains and hygroaurins.