Deep intravital brain tumor imaging enabled by tailored three-photon microscopy and analysis
M. C. Schubert, S. J. Soyka, A. Tamimi, E. Maus, R. Denninger, N. Wissmann, E. Reyhan, S. K. Tetzlaff, C. Beretta, M. Drumm, J. Schroers, A. Steffens, J. Walshon, K. McCortney, S. Heiland, , V. Venkataramani
This paper introduces Deep3P, a three-photon microscopy and AI analysis method that enables deep intravital imaging of glioblastoma in mouse brains, revealing new insights into tumor invasion routes and white matter disruption.
bioRxiv · Jun 17, 2023Cancer Biology