Simultaneous aerosol and intra-muscular immunization with influenza vaccine induces powerful protective local T cell and systemic Ab immune responses in pigs
V. Martini, B. Paudyal, T. Chrun, A. McNee, M. Edmans, E. Maze, B. Clark, A. Nunez, G. Dolton, A. Sewell, P. Beverley, R. MacLoughlin, A. Townsend, E. Tchilian
This study evaluates simultaneous aerosol and intramuscular influenza vaccination in pigs, finding that combined immunization induces both strong antibody and local T cell responses, leading to better virus control.
bioRxiv · Sep 10, 2020Immunology