Author

T. Chrun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:plant (other)· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:chicken / avian· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

E. Tchilian· 4 shared A. Mcnee· 3 shared V. Martini· 3 shared A. Nunez· 2 shared A. Townsend· 2 shared B. Paudyal· 2 shared E. A. Maze· 2 shared M. Edmans· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersImmunology

E. Tchilian

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Simultaneous infection with porcine reproductive and respiratory syndrome and influenza viruses abrogates clinical protection induced by live attenuated porcine reproductive and respiratory syndrome vaccination

T. Chrun, E. A. Maze, E. Vatzia, V. Martini, B. Paudyal, M. Edmans, A. Mcnee, T. Manjegowda, F. J. Salguero, N. Wanasen, S. Koonpaew, S. P. Graham, E. Tchilian

This study shows that co-infection with PRRSV-2 and H3N2 virus reduces the protective effect of PRRS MLV vaccination against clinical disease.

bioRxiv · Aug 12, 2021Immunology

Identification and phenotype of MAIT cells in cattle and their response to bacterial infections

M. D. Edmans, T. K. Connelley, S. Jayaraman, C. vrettou, M. Vordermeier, J. Y. W. Mak, L. Liu, D. P. Fairlie, E. A. Maze, T. Chrun, P. Klenerman, S. B. G. Eckle, E. Tchilian, L. Benedictus

This study identifies and characterizes MAIT cells in cattle, showing their functional response to bacterial infections and their enrichment in mucosal tissues.

bioRxiv · Nov 9, 2020Immunology

Simultaneous aerosol and intra-muscular immunization with influenza vaccine induces powerful protective local T cell and systemic Ab immune responses in pigs

V. Martini, B. Paudyal, T. Chrun, A. McNee, M. Edmans, E. Maze, B. Clark, A. Nunez, G. Dolton, A. Sewell, P. Beverley, R. MacLoughlin, A. Townsend, E. Tchilian

This study evaluates simultaneous aerosol and intramuscular influenza vaccination in pigs, finding that combined immunization induces both strong antibody and local T cell responses, leading to better virus control.

bioRxiv · Sep 10, 2020Immunology

Establishment of a pig influenza challenge model for evaluation of monoclonal antibody delivery platforms

A. McNee, T. Smith, B. Holzer, C. Becky, E. Bessell, G. Guibinga, H. Brown, K. Schultheis, P. Fisher, S. Ramos, A. Nunez, M. Bernard, V. Martini, T. Chrun, Y. Xiao, , E. Tchilian

This study establishes a pig influenza model to evaluate monoclonal antibody efficacy against H1N1, showing dose-dependent reduction in viral load and lung pathology.

bioRxiv · Mar 12, 2020Immunology