Prophylactic inhibition of colonization by Streptococcus pneumoniae with the secondary bile acid metabolite deoxycholic acid
J. E. Vidal, M. N. Wier, U. Angulo-Zamudio, E. McDevitt, A. G. Vidal, B. Alibayov, A. Scasny, S. M. Wong, B. J. Akerley, L. S. McDaniel
This study shows deoxycholic acid eradicates Streptococcus pneumoniae colonization in vitro and in vivo, with no observed resistance.
bioRxiv · May 17, 2021Microbiology