Hallmarks of tumor-experienced T cells are absent in multiple myeloma patients from diagnosis through maintenance therapy
C. Shasha, D. R. Glass, E. Moelhman, L. Islas, Y. Tian, G. L. Szeto, T. Peng, X. Song, M. Wurscher, T. F. Bumol, T. R. Torgerson, P. D. Greenberg, D. J. Green, E. W. Newell
The paper profiles CD8+ T cells in multiple myeloma patients to assess tumor reactivity and exhaustion, finding no evidence of tumor-experienced T cells with hallmark exhaustion or activation features.
bioRxiv · Jun 3, 2024 · PreprintImmunology