ImmunologybioRxiv
Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in ovarian cancer enhances therapeutic efficacy
K. G. Anderson, S. K. Oda, B. M. Bates…·P. D. Greenberg
This paper enhances ovarian cancer T cell therapy by engineering T cells to co-opt Fas ligand-mediated death signaling into pro-survival signals, improving persistence and therapeutic efficacy.
DOI 10.1136/jitc-2021-003959