In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris
J. M. Rybak, K. S. Barker, J. F. Munoz, J. E. Parker, S. Ahmad, E. Mokaddas, A. Abdullah, R. S. Elhagracy, S. L. Kelly, C. A. Cuomo, P. D. Rogers
The paper identifies a mutation in the ERG6 gene as the first mechanism of amphotericin B resistance in Candida auris, observed during in vivo treatment.
bioRxiv · Oct 8, 2021Microbiology