Author

J. M. Rybak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

C. A. Cuomo· 2 shared J. F. Munoz· 2 shared K. S. Barker· 2 shared P. D. Rogers· 2 shared S. L. Kelly· 2 shared A. Abdullah· 1 shared B. D. Esquivel· 1 shared C. F. Ancajas· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

C. A. Cuomo

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Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintNov 1, 2023

The small molecule CBR-5884 inhibits the Candida albicans phosphatidylserine synthase

Y. Zhou, G. A. Phelps, M. M. Mangrum…·T. B. B. Reynolds

The paper identifies CBR-5884 as a potent inhibitor of Candida albicans Cho1, showing fungistatic effects and disrupting in vivo Cho1 function.

DOI 10.1101/2023.11.01.565123

C. elegansexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivOct 8, 2021

In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris

J. M. Rybak, K. S. Barker, J. F. Munoz…·P. D. Rogers

The paper identifies a mutation in the ERG6 gene as the first mechanism of amphotericin B resistance in Candida auris, observed during in vivo treatment.

DOI 10.1016/j.cmi.2021.11.024

C. eleganswhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivFeb 18, 2020

Mutations in TAC1B: a novel genetic determinant of clinical fluconazole resistance in C. auris

J. M. Rybak, J. F. Munoz, K. S. Barker…·P. D. Rogers

This paper identifies mutations in TAC1B as a novel genetic determinant of clinical fluconazole resistance in C. auris, showing their contribution to resistance through increased CDR1 expression and functional validation.

DOI 10.1128/mbio.00365-20

C. elegansexperimental assay

𝕏 PostBluesky