MicrobiologybioRxiv
In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris
J. M. Rybak, K. S. Barker, J. F. Munoz…·P. D. Rogers
The paper identifies a mutation in the ERG6 gene as the first mechanism of amphotericin B resistance in Candida auris, observed during in vivo treatment.
DOI 10.1016/j.cmi.2021.11.024