Myofiber / pro-inflammatory macrophage interplay controls muscle damage in mdx mice
M. Saclier, S. Ben Larbi, E. Moulin, R. Mounier, B. Chazaud, G. Juban
This study shows that dystrophic myofibers promote pro-inflammatory macrophage polarization, leading to muscle damage, and that H2S donors can reduce inflammation and fibrosis in mdx mice.
bioRxiv · Dec 28, 2020 · PreprintCell Biology