Single-cell characterisation of the hematopoietic bone marrow interactome in health and disease
S. Ennis, A. Conforte, E. O'Reilly, T. Cichocka, S. Pal Dhami, P. Nicholson, P. Krebs, P. O Broin, E. Szegezdi
The paper characterizes the hematopoietic bone marrow interactome in health and acute myeloid leukemia using single-cell gene expression data, revealing dysregulated ligand-receptor interactions and the role of TGFB1 in AML progression.
bioRxiv · May 13, 2022 · PreprintCancer Biology