M. Attiyeh

This study identifies the base excision repair pathway as a regulator of transcription-replication conflicts in pancreatic ductal adenocarcinoma, showing that its inhibition enhances DNA damage and reduces cell proliferation.

This study uses whole genome sequencing to show that relapsed multiple myeloma exhibits accelerated systemic seeding driven by chemotherapy-induced mutations and clonal expansion of single myeloma cells.

This study identifies genetic features of recurrent pancreatic cancer through sequencing and finds that treatment-induced genetic changes and potential second primary tumors influence recurrence.