β-Coronaviruses use lysosomal organelles for cellular egress.
N. Altan-Bonnet, G. Y. Altan-Bonnet, S. Ghosh, T. Dellibovi-Ragheb, E. Pak, Q. Qiu, M. Fisher, P. Takvorian, C. Bleck, V. Hsu, A. Fehr, S. Perlman, M. Straus, G. Whittaker, C. A. de Haan
This study shows β-coronaviruses exit cells via lysosomal trafficking, not the secretory pathway, and identifies Arl8b as a regulator of this process.
bioRxiv · Jul 25, 2020 · PreprintMicrobiology