Author

M. Straus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Whittaker· 2 shared A. Fehr· 1 shared C. A. de Haan· 1 shared C. Bleck· 1 shared E. Pak· 1 shared G. Khelashvili· 1 shared G. R. Whittaker· 1 shared G. Y. Altan-Bonnet· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

G. Whittaker

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A mechanistic understanding of the modes of Ca2+ ion binding to the SARS-CoV-1 fusion peptide and their role in the dynamics of host membrane penetration

J. Carten, G. Khelashvili, M. K. Bidon, M. Straus, T. Tang, J. A. Jaimes, H. Weinstein, G. Whittaker, S. Daniel

This study identifies specific Ca2+ binding residue pairs in SARS-CoV-1 fusion peptide that promote or inhibit membrane insertion through molecular dynamics and biological assays.

bioRxiv · Mar 3, 2022 · PreprintMicrobiology

β-Coronaviruses use lysosomal organelles for cellular egress.

N. Altan-Bonnet, G. Y. Altan-Bonnet, S. Ghosh, T. Dellibovi-Ragheb, E. Pak, Q. Qiu, M. Fisher, P. Takvorian, C. Bleck, V. Hsu, A. Fehr, S. Perlman, M. Straus, G. Whittaker, C. A. de Haan

This study shows β-coronaviruses exit cells via lysosomal trafficking, not the secretory pathway, and identifies Arl8b as a regulator of this process.

bioRxiv · Jul 25, 2020 · PreprintMicrobiology

SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses

M. Straus, J. T. Kinder, M. Segall, R. E. Dutch, G. R. Whittaker

This study shows SPINT2 inhibits proteases needed for activation of influenza and metapneumoviruses, reducing viral growth in cell culture.

Virology · Apr 1, 2020Peer-reviewedMicrobiology