Author

E. Poole

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

J. Sinclair· 2 shared A. Binyamin· 1 shared A. Boshkov· 1 shared A. Nachshon· 1 shared B. A. Krishna· 1 shared B. Krishna· 1 shared C. M. O'Connor· 1 shared E. G. Elder· 1 shared

Activity by Year

2017-2019 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

J. Sinclair

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2 papers

Recent·Most cited

Interferon-responsive genes are targeted during the establishment of human cytomegalovirus latency

E. G. Elder, B. A. Krishna, J. Williamson, E. Y. Lim, E. Poole, G. X. Sedikides, C. M. O'Connor, M. Wills, P. J. Lehner, J. Sinclair

This study identifies that US28 downregulates interferon-inducible genes during HCMV latency, with IFI16 suppression enhancing viral gene expression via NF-κB.

bioRxiv · Oct 4, 2019Microbiology

Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing

M. Shnayder, A. Nachshon, B. Krishna, E. Poole, A. Boshkov, A. Binyamin, I. Maza, J. Sinclair, M. Schwartz, N. Stern-Ginossar

This study uses single-cell RNA sequencing to analyze HCMV latency and finds no evidence of a restricted latency-associated gene expression program, instead showing gene expression patterns similar to late lytic stages at lower levels.

bioRxiv · Nov 3, 2017Microbiology