Author

E. Potapenko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:mouse· 3 Assay:electrophysiology· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. J. Merrins· 3 shared T. Ho· 3 shared H. R. Foster· 2 shared H. R. VanDeusen· 2 shared R. G. Kibbey· 2 shared R. L. Cardone· 2 shared S. L. Lewandowski· 2 shared C. A. Moore· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCell Biology

M. J. Merrins

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A plasma membrane-associated glycolytic metabolon is functionally coupled to KATP channels in pancreatic α and β cells from humans and mice

T. Ho, E. Potapenko, D. B. Davis, M. J. Merrins

The paper demonstrates a glycolytic metabolon on the plasma membrane that directly controls KATP channels in pancreatic α and β cells from humans and mice through ATP/ADP and NAD+/NADH cycles.

bioRxiv · Oct 6, 2022 · PreprintBiochemistry

The isoforms of pyruvate kinase act as nutrient sensors for the β-cell KATP channel

H. R. Foster, T. Ho, E. Potapenko, S. M. Sdao, S. L. Lewandowski, H. R. VanDeusen, S. M. Davidson, R. L. Cardone, M. Prentki, R. G. Kibbey, M. J. Merrins

This study identifies PKm1 and PKm2 as nutrient sensors that regulate β-cell KATP channels through mitochondrial PEP, influencing insulin secretion and Ca2+ oscillations.

bioRxiv · Feb 9, 2022 · PreprintCell Biology

The Role of Potassium and Host Calcium Signaling in Toxoplasma gondii egress

S. A. Vella, C. A. Moore, Z.-H. Li, M. A. Hortua Triana, E. Potapenko, S. N. Moreno

This study investigates how potassium and calcium signaling in host cells influence Toxoplasma gondii egress, showing that both intracellular and extracellular Ca2+ sources are required and that low potassium modulates egress.

bioRxiv · Mar 6, 2020Microbiology

Pyruvate kinase controls signal strength in the insulin secretory pathway

S. L. Lewandowski, R. L. Cardone, H. R. Foster, T. Ho, E. Potapenko, C. Poudel, H. R. VanDeusen, T. C. Alves, X. Zhao, M. E. Capozzi, I. Jahan, C. S. Nunemaker, J. E. Campbell, C. J. Thomas, R. G. Kibbey, M. J. Merrins

This paper shows pyruvate kinase (PK) controls insulin secretion by regulating ATP/ADP ratios and mitochondrial metabolism in beta-cells, suggesting PK activation as a potential diabetes therapy.

bioRxiv · Jan 15, 2020Cell Biology