Modified histone peptides uniquely tune the material properties of HP1α condensates.
P. Deshpande, E. Prentice, A. Vidal Ceballos, P. Casaccia, S. Elbaum-Garfinkle
This paper shows that H3K9me3 histone peptides modulate the viscoelastic properties of HP1α-DNA condensates in a concentration-dependent manner, linking epigenetic marks to the dynamic behavior of heterochromatin.
bioRxiv · Feb 7, 2024 · PreprintBiophysics