Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma
E. Aliagas, A. Alay, M. Martinez-Iniesta, M. Hernandez-Madrigal, D. Cordero, M. Gausachs, E. Pros, M. Saigi, S. Busacca, A. Sharkley, A. Dawson, R. Palmero, S. Padrones, S. Aso, I. Escobar, , E. Nadal
This study evaluates CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma, finding they reduce tumor growth and improve survival by inducing cell cycle arrest and senescence.
bioRxiv · Feb 8, 2021 · PreprintCancer Biology