Author

E. R. Smithwick

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Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bhagi-Damodaran· 2 shared A. Rama Damodaran· 2 shared J. J. Dalluge· 1 shared R. H. Wilson· 1 shared S. Chatterjee· 1 shared Y. Pu· 1 shared

Activity by Year

2023-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

A. Bhagi-Damodaran

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2 papers

Recent·Most cited

Equilibrium dialysis with HPLC detection to measure substrate binding affinity of a non-heme iron halogenase

E. R. Smithwick, A. Bhagi-Damodaran, A. Rama Damodaran

The paper describes a method using equilibrium dialysis and HPLC to measure the substrate binding affinity (Kd) of the non-heme iron halogenase BesD for lysine.

bioRxiv · Apr 3, 2024 · PreprintBiochemistry

Electrostatically regulated active site assembly governs reactivity in non-heme iron halogenases

E. R. Smithwick, R. H. Wilson, S. Chatterjee, Y. Pu, J. J. Dalluge, A. Rama Damodaran, A. Bhagi-Damodaran

This study investigates how anion and substrate binding cooperatively regulate reactivity in non-heme iron halogenases through electrostatic interactions in the active site.

bioRxiv · May 25, 2023 · PreprintBiochemistry