A. Bhagi-Damodaran

This study reprograms hypoxia signaling by engineering PHD2 to enhance its catalytic efficiency, leading to reduced HIF-1 and hypoxia response transcripts under low oxygen conditions.

This paper investigates ATP binding in the short ATP-lid of DosS CA domain, showing it binds ATP under physiological conditions and revealing conformational flexibility affected by zinc concentration.

This study investigates how anion and substrate binding cooperatively regulate reactivity in non-heme iron halogenases through electrostatic interactions in the active site.