Distinguishing Mechanisms Underlying EMT Tristability
D. Jia, M. K. Jolly, S. C. Tripathi, P. D. Hollander, B. Huang, M. Lu, M. Celiktas, E. Ramirez-Pena, E. Ben-Jacob, J. N. Onuchic, S. M. Hanash, S. A. Mani, H. Levine
The paper uses experimental and theoretical approaches to evaluate two models of EMT dynamics, finding experimental evidence supporting the ternary chimera switch model over the cascading bistable switches model.
bioRxiv · Jan 6, 2017Cancer Biology