Multi-modal Efficacy of a Chimeric Vesiculovirus Expressing the Morreton Glycoprotein in Sarcoma
C. Dumbauld, O. Barro, N. M. Elliott, Y. Zhou, M. Gabere, E. Raupach, A. T. Baker, M. T. Barrett, K. Buetow, B. Jacobs, M. Seetharam, M. Borad, B. M. Nagalo
This study develops a chimeric vesiculovirus (VMG) expressing MorV glycoprotein, showing anti-tumor effects in sarcoma models with in vitro efficacy and in vivo tumor reduction.
bioRxiv · Sep 18, 2022 · PreprintImmunology