Structural and functional analysis of Pseudomonas aeruginosa PelA provides insight into the modification of the Pel exopolysaccharide
J. C. Van Loon, F. Le Mauff, M. Vargas, S. Gilbert, R. Pfoh, Z. A. Morrison, E. Razvi, M. Nitz, D. Sheppard, P. L. Howell
This study determines the structure of PelA and shows it modifies Pel through deacetylation and hydrolysis, with PelAB interaction enhancing deacetylation and guiding export.
bioRxiv · Jun 28, 2024Microbiology