The polyamine transporter ATP13A3 mediates DFMO-induced polyamine uptake in neuroblastoma
M. Azfar, W. Gao, C. Van den Haute, L. Xiao, M. Karsa, R. Pandher, E. Ronca, A. Bongers, A. Karsa, D. Spurling, X. Guo, C. Mayoh, M. R. Burns, S. H. L. Verhelst, M. D. Norris, , K. Somers
This study identifies ATP13A3 as a polyamine transporter mediating DFMO-induced polyamine uptake in neuroblastoma, highlighting it as a therapeutic target.
bioRxiv · Feb 20, 2024 · PreprintCancer Biology