Author

E. Roth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. Mielenz· 2 shared M. Hauke· 2 shared S. R. Schulz· 2 shared W. Schuh· 2 shared A. Burchert· 1 shared A. Ensser· 1 shared A. M. Hartmann· 1 shared A. Neubauer· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

D. Mielenz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The microRNA processing subunit DGCR8 is required for a T cell-dependent germinal center response

D. Patrick, J. Meinzinger, S. R. Schulz, J. Corte-Real, M. Hauke, E. Roth, W. Schuh, D. Mielenz, J. Wittmann, H.-M. Jäck, K. Pracht

This study shows that DGCR8 is essential for T cell-dependent germinal center responses and antibody production, but not for B-1 cell functions.

bioRxiv · Jul 31, 2022Immunology

IRF4 deficiency vulnerates B cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity

D. Das Gupta, C. Paul, N. Samel, M. Bieringer, D. Staudenraus, F. Marini, H. Raifer, L. Menke, L. Hansal, B. Camara, E. Roth, P. Daum, M. Wanzel, M. Mernberger, A. Nist, , M. Lohoff

This study shows IRF4 deficiency leads to B cell leukemia via Jak3 mutations that increase IL-7 sensitivity, and JAK inhibition improves survival in a mouse model.

bioRxiv · Feb 16, 2022 · PreprintCancer Biology

A pair of non-competing neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model

A. S. Peter, E. Roth, S. R. Schulz, K. Fraedrich, T. Steinmetz, D. Damm, M. Hauke, E. Richel, S. Mueller-Schmucker, K. Habenicht, V. Eberlein, L. Issmail, N. Uhlig, S. Dolles, E. Gruner, , H.-M. Jack

The paper identifies two clusters of non-competing neutralizing antibodies against SARS-CoV-2 that protect mice from infection and weight loss.

bioRxiv · Apr 16, 2021 · PreprintImmunology